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Recombinant 2019-nCoV Spike protein S1 subunit, receptor-binding domain (RBD) (319-541) (L452R) was expressed in CHO cells using a C-terminal his tag.
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C19SD-G235H-10 |
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100 ug
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基因别名：
2019-nCoV RBD, SARS-CoV-2 spike RBD, novel coronavirus spike RBD, nCov spike RBD.
Genbank编号：
参考文献：
1. Lan J, et al: Crystal structure of the 2019-nCov spike receptor-binding domain bound with the ACE2 receptor. bioRxiv. doi: https://doi.org/10.1101/2020.02.19.956235.
2. Mascola JR, et al: SARS-CoV-2 viral variants - Tackling a moving target. JAMA. Published online February 11, 2021. doi:10.1001/jama.2021.2088.
3. Starr TN, et al: Molecular dynamic simulation reveals E484K mutation enhances spike RBD-ACE2 affinity and the combination of E484K, K417N and N501Y mutations (501Y.V2 variant) induces conformational change greater than N501Y mutant alone, potentially resulting in an escape mutant. Cell. 2020, 182(5):1295-1310.
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Acute Respiratory Distress Syndrome , Cardiovascular Disease, Cell Cycle, Cellular Stress, COVID19, Inflammation, Lung Diseases , Neurobiology, severe acute respiratory syndrome coronavirus 2 , Virology
2019-nCoV Spike protein S1 (D614G), C19S1-G231H