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Human IA-2 (ICA 512) Antigen

Recombinant Human IA-2 (ICA 512) Antigen was expressed by baculovirus in Sf9 insect cells and purified by affinity chromatography using a His tag.

HIA01-F23H-01

100 ug 1 mg Bulk

参考文献:

1. Notkins AL, et al. IA-2 and IA-2 beta are major autoantigens in IDDM and the precursors of the 40 kDa and 37 kDa tryptic fragments. J Autoimmun. 1996 Oct;9(5):677-82.

2. Solimena M, et al. ICA 512, an autoantigen of type I diabetes, is an intrinsic membrane protein of neurosecretory granules. EMBO J. 1996 May 1;15(9):2102-14.

3. Verge CF, et al. Prediction of type I diabetes in first-degree relatives using a combination of insulin, GAD, and ICA512bdc/IA-2 autoantibodies. Diabetes. 1996 Jul;45(7):926-33.




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