概述:

Bacteriophage T4 gene 32 protein (gp32) is a single-stranded DNA binding protein with key role in DNA replication, recombination, and repair. T4 gp32 is a zinc metalloprotein with three functional domains: the N-terminal basic domain, the core domain and the C-terminal acidic domain. The ssDNA binding site lies in the core domain. In vitro, T4 gp32 binds cooperatively to single stranded DNA and stimulates cell-free DNA synthesis directed by the T4-encoded DNA polymerase (1,2)

基因别名：

ss-DNA binding protein (g32), SSB protein, Helix-destabilizing protein

Genbank编号：

J02513.1

参考文献：

1. Jordan, C.S. et al: Regulation of the bacteriophage T4 Dda helicase by Gp32 single-stranded DNA-binding protein. DNA Repair (Amst), 2015; 25: 41-53. 2. Pant, K. et al: The role of the C-domain of bacteriophage T4 gene 32 protein in ssDNA binding and dsDNA helix-destabilization: Kinetic, single-molecule, and cross-linking studies. PLoS One. 2018; 10:13(4):e0194357.