Recombinant full-length T4 UvsY Protein from Escherichia virus T4 was expressed in E. coli using an N-terminal His-tag.
T4SY-C501H-50 |
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概述:
UvsY is a bacteriophage T4 recombination mediator protein (RMP) which promotes homologous recombination. UvsY exists in solution predominantly as a hexamer, and binds to ssDNA in this form. UvsY facilitates assembly of presynaptic filaments by loading UvsX recombinase onto ssDNA and the concomitant displacement of Gp32 ssDNA-binding protein from ssDNA (1,2).
基因别名:
Bacteriophage T4 DNA repair gene uvsY, recombination protein uvsY
Genbank编号:
参考文献:
1. Liu, J. et al: Mechanism of presynaptic filament stabilization by the bacteriophage T4 UvsY recombination mediator protein. Biochemistry, 2006; 45(17): 5493–5502. 2. Liu, J. et al: Assembly and dynamics of the bacteriophage T4 homologous recombination machinery. Virol J, 2010; 7:357.
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